If you are unfamiliar with what to monitor in MySQL, starting with looking at what popular Monitoring products monitor. For example, the following is the list of MySQL Cacti Plugin measurements.
Innodb Buffer Pool Activity
- Pages Created
- Pages Written
- Pages Read
Innodb Buffer Pool Pages
- Pool Size
- Database Pages
- Free Pages
- Modified Pages
Inoodb File I/O
- File Reads
- Files Writes
- Log Writes
- File Fsyncs
Innodb Pending I/O
- Aio Log Ios
- Aio Sync ios
- Buffer Pool Flushes
- Chkp Writes
- Ibuf Aio Reads
- Log Flushes
- Log Writes
- Normal Aio Reads …