MySQL theoretical limits are known and they can be found in the manual, they include:
MyISAM permits data and index files to grow up to 256 TiB by default, but this limit can be changed up to the maximum permissible size of 65,536 TiB (256^7 − 1 bytes). The maximum tablespace size depends on the InnoDB page size: 64 TiB for 16 KiB pages.(The maximum tablespace size is also the maximum size for a